Green Chemistry in Pharmaceutical Industries

Green chemistry is being employed to develop revolutionary drug delivery methods that are more effective and less toxic and could benefit millions of patients. Phosphoramidite-based, solid-phase synthesis of antisense oligonucleotides has been modified to accommodate principles of green chemistry by eliminating the use and generation of toxic materials and allowing reuse of valuable materials such as amidites, solid-support and protecting groups, thus improving the atom economy and cost-efficiency,