GREEN CHEMISTRY

There are number of approaches that can be used to support chemical risk assessment. Ideally, predictive tools identify hazards to be avoided; for example, it may be possible to identify a compound property or structural features that are associated with adverse effects. Such computational tools that exploit existing toxicology information can be used to ascertain potential relationships between chemical space and toxicological response. The outputs from these analyses can be used to define project-specific, toxicology experiments to determine if the predicted toxicities are real and so influence compound design.